Mapping protein interactions using a new chemical method.
A systems-level approach to decipher the protein interactome.
This study is exploring how proteins work together inside cells, using a special technique to see exactly where and when these interactions happen, which can help us better understand how our bodies function.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11014633 on NIH RePORTER |
What this research studies
This research investigates how proteins interact within cells, which is crucial for understanding biological processes. It employs a novel technique called Fast Photochemical Oxidation and Capture by Suzuki (FPICS) to identify and map these interactions at a high resolution. By using halogenated molecules as markers, the research aims to pinpoint where and when these interactions occur, enhancing our understanding of cellular functions. This approach combines advanced laser technology and mass spectrometry to capture detailed interaction data.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to protein interactions, such as certain cancers or metabolic disorders.
Not a fit: Patients with conditions unrelated to protein interactions or those not requiring detailed molecular analysis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding diseases at a molecular level, potentially informing new therapeutic strategies.
How similar studies have performed: Similar research approaches have shown promise in mapping protein interactions, but this specific method is considered novel and untested.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Backus, Keriann Marie — University of California Los Angeles
- Study coordinator: Backus, Keriann Marie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.