Mapping protein and gene activity in kidney diseases
Spatial Mapping of Proteomic and Transcriptional Signatures in Kidney Disease
This study is looking at kidney tissue samples to understand what causes sudden kidney problems and long-term kidney disease, with the goal of finding better ways to diagnose and treat people who are dealing with these issues.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10892068 on NIH RePORTER |
What this research studies
This research investigates the underlying causes of acute kidney injury (AKI) and chronic kidney disease (CKD) by analyzing kidney tissue samples. Using advanced techniques that combine proteomics and transcriptomics, the study aims to identify specific cellular and molecular patterns associated with these conditions. By examining kidney biopsies from the Kidney Precision Medicine Project, researchers hope to gain insights that could lead to better diagnostic tools and treatment options for patients suffering from kidney diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with acute kidney injury or chronic kidney disease.
Not a fit: Patients with kidney diseases that are not classified as AKI or CKD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new diagnostic methods and targeted therapies for kidney diseases, improving patient outcomes.
How similar studies have performed: Similar multi-omics approaches have shown promise in other fields, such as cancer biology, suggesting potential for success in kidney disease research.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Thurman, Joshua M — University of Colorado Denver
- Study coordinator: Thurman, Joshua M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.