Mapping Ovarian Cancer in Three Dimensions
3D Spatial Multi-Omics Profiling of Ovarian Cancer
This research aims to create a detailed 3D map of ovarian cancer to understand why some patients don't respond to treatment.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11174444 on NIH RePORTER |
What this research studies
High-grade serous ovarian cancer (HGSOC) is often diagnosed late, and a subset of patients does not respond well to initial treatments. This project will build a detailed three-dimensional map of ovarian cancer using advanced molecular and cellular techniques from patient samples. By understanding how the cancer spreads and resists treatment in three dimensions, we hope to find new ways to improve treatment effectiveness. This work involves experts from different fields collaborating to integrate complex data, ultimately forming an Ovarian Cancer Atlas.
Who could benefit from this research
Good fit: This research uses samples from patients diagnosed with advanced high-grade serous ovarian cancer.
Not a fit: Patients with other types of cancer or those not diagnosed with advanced high-grade serous ovarian cancer may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new strategies for treating advanced ovarian cancer and improving patient survival.
How similar studies have performed: While 3D mapping techniques are emerging, this specific comprehensive 3D ovarian cancer atlas using multi-omics is a novel and integrated approach.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Mok, Samuel C — University of Tx Md Anderson Can Ctr
- Study coordinator: Mok, Samuel C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.