Mapping nerve circuits that control gut movement
Identification of enteric nerve circuits controlling gut motility
This study is looking at how the nerves in your gut work to help with digestion and nutrient absorption, using animals like mice and guinea pigs to find out more about how these nerves interact, which could help us understand and treat digestive problems better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan State University NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project ID | NIH-10652992 on NIH RePORTER |
What this research studies
This research investigates the enteric nervous system, which regulates gut motility and nutrient absorption. By using advanced techniques like antibody labeling and gene editing, the study aims to identify specific nerve pathways and their functions in the gastrointestinal tract. Researchers will utilize animal models, including mice and guinea pigs, to explore how different types of neurons interact and contribute to gut health. This work could lead to a better understanding of digestive disorders and potential new treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing gastrointestinal motility disorders or related digestive issues.
Not a fit: Patients with non-gastrointestinal conditions or those not experiencing gut motility issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for gastrointestinal disorders by enhancing our understanding of gut motility regulation.
How similar studies have performed: Other research has shown promising results in mapping neural circuits in the enteric nervous system, suggesting that this approach could yield valuable insights.
Where this research is happening
East Lansing, United States
- Michigan State University — East Lansing, United States (Active)
Researchers
- Principal investigator: Galligan, James J. — Michigan State University
- Study coordinator: Galligan, James J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.