Mapping Kidney Disease Pathways
Spatial Multi-Omics to Profile Metabolic Pathways for Kidney Disease
This project uses advanced imaging to create a detailed map of how kidney disease affects the body's chemistry in human kidney tissue.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-11174318 on NIH RePORTER |
What this research studies
Our team is part of the Kidney Precision Medicine Project, which aims to build a comprehensive map of human kidney tissue. We use special imaging techniques to look at hundreds of tiny molecules, like fats and sugars, within kidney biopsies. This helps us understand how kidney disease changes the chemical processes in different parts of the kidney. By combining these images with other information, we can learn more about how kidney disease develops and progresses at a very detailed level.
Who could benefit from this research
Good fit: Patients with acute kidney failure or other kidney conditions could eventually benefit from the knowledge gained from this detailed tissue analysis.
Not a fit: Patients who do not have kidney disease or related conditions may not directly benefit from this specific research.
Why it matters
Potential benefit: This work could lead to a better understanding of kidney disease, potentially helping doctors find new ways to diagnose and treat patients more precisely in the future.
How similar studies have performed: The methods used for analyzing kidney tissue have been validated and approved within the larger Kidney Precision Medicine Project, building on previous successful development.
Where this research is happening
San Antonio, United States
- University of Texas Hlth Science Center — San Antonio, United States (Active)
Researchers
- Principal investigator: Sharma, Kumar — University of Texas Hlth Science Center
- Study coordinator: Sharma, Kumar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.