Mapping Kidney Disease Changes at a Detailed Level
Spatial Mapping of Proteomic and Transcriptional Signatures in Kidney Disease
['FUNDING_U01'] · UNIVERSITY OF COLORADO DENVER · NIH-11174326
This project aims to understand the specific changes happening in kidney cells of patients with acute and chronic kidney disease to find new ways to diagnose and treat these conditions.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-11174326 on ClinicalTrials.gov |
What this research studies
Acute and chronic kidney diseases are common and serious, but current tests don't tell us enough about what's truly causing the damage. We want to look closely at kidney tissue from patients to see the exact cellular and molecular changes occurring. By using advanced technologies that map proteins and genetic activity in specific areas of the kidney, we hope to uncover new insights. This detailed understanding could help us develop better ways to identify and treat kidney problems in the future.
Who could benefit from this research
Good fit: This research uses existing kidney tissue samples from patients with acute and chronic kidney disease, particularly those from the Kidney Precision Medicine Project.
Not a fit: Patients who do not have acute or chronic kidney disease or whose tissue samples are not part of the Kidney Precision Medicine Project would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to more precise diagnostic tools and new treatment options for patients suffering from acute and chronic kidney disease.
How similar studies have performed: Multi-omics analyses have shown significant success in other fields, like cancer biology, by revealing detailed cellular and molecular patterns.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: THURMAN, JOSHUA M — UNIVERSITY OF COLORADO DENVER
- Study coordinator: THURMAN, JOSHUA M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.