Mapping immune cells in blood to understand organ health
High dimensional atlas of circulating neutrophils as reporters of solid organ functional status
This work aims to create a detailed map of immune cells in your blood to help doctors detect serious organ diseases earlier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11118906 on NIH RePORTER |
What this research studies
Many serious organ diseases often go unnoticed until they are advanced, making them harder to treat. This project looks at neutrophils, which are common immune cells in your blood, to see if they carry clues about the health of your organs. By understanding these cells better, we hope to find a simple blood test that can tell us about the status of many organs at once. This could help identify diseases much sooner, when treatments are more effective.
Who could benefit from this research
Good fit: This foundational work is not directly recruiting patients for a clinical trial, but future studies stemming from this research may seek individuals with or at risk for chronic solid organ diseases.
Not a fit: Patients without chronic solid organ diseases or those not interested in contributing to early diagnostic research may not directly benefit from this specific grant's outcomes.
Why it matters
Potential benefit: If successful, this could lead to new, non-invasive blood tests that detect chronic organ diseases earlier, allowing for timely treatment or preventive measures.
How similar studies have performed: While the concept of using immune cells as disease reporters is gaining traction, creating a comprehensive 'atlas' for multiple organ systems is a novel and largely untested approach.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Okwan-Duodu, Derick — Stanford University
- Study coordinator: Okwan-Duodu, Derick
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.