Mapping immune and cell networks in very early onset inflammatory bowel disease
Identifying Immune and Epithelial Network Signatures in Very Early Onset Inflammatory Bowel Disease
This study is looking at the immune and skin cells in young children under 6 who have very early onset inflammatory bowel disease, to better understand the condition and find new treatments, and we need your help by providing blood and tissue samples.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10892230 on NIH RePORTER |
What this research studies
This research aims to create a detailed atlas of immune and epithelial cells in children with very early onset inflammatory bowel disease (VEOIBD), particularly those under 6 years old. By analyzing these cells at a single-cell level, the project seeks to understand the disease's underlying mechanisms and identify potential genetic causes. The research involves collaboration among experts in various fields, including immune profiling and data analysis, to develop targeted therapies for affected patients. Patients will contribute to this effort by providing blood and tissue samples for analysis.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under 6 years old diagnosed with very early onset inflammatory bowel disease.
Not a fit: Patients over the age of 6 or those without a diagnosis of very early onset inflammatory bowel disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for children suffering from very early onset inflammatory bowel disease.
How similar studies have performed: Other research has shown promise in using multi-omic approaches to understand complex diseases, suggesting potential for success in this novel investigation.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Snapper, Scott B — Boston Children's Hospital
- Study coordinator: Snapper, Scott B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.