Mapping how the immune system fights paramyxoviruses
Official title: Genetic and Structural Basis for Virus Neutralization of Paramyxoviruses
Funded at Vanderbilt University Medical Center · NIH-11196678 · Data updated 2026-11-12
This study is looking at how our immune system fights off certain viruses called paramyxoviruses, which can make people sick, to help create better treatments and vaccines for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | September 16, 2024 |
| Project end | September 15, 2025 |
| Funding year | 2024 |
| Award (this year) | $1,395,030 |
| NIH project number | 75N93024C00072-0-9999-1 |
| Project ID | NIH-11196678 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who are at risk of infections from paramyxoviruses or those who may benefit from enhanced immunity against these viruses.
✕Less likely to help
Patients who are not at risk for paramyxovirus infections or those with existing immunity may not receive significant benefits from this research.
What this research studies
This research investigates how the human immune system recognizes and neutralizes paramyxoviruses, a family of RNA viruses. By mapping the specific parts of these viruses that antibodies target, the study aims to enhance our understanding of immunity against both zoonotic and endemic strains. The findings could lead to the development of new therapeutic antibodies or vaccines to better protect individuals from these viral infections.
Why it matters
Potential benefit: If successful, this research could lead to improved vaccines and treatments for infections caused by paramyxoviruses.
How similar studies have gone: Other research has shown success in mapping immune responses to various viruses, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.