Mapping how proteins interact with biomolecules using advanced light technology

Optically Gated Discovery of Protein-Biomolecule Interactions

NIH-funded research Weill Medical Coll of Cornell Univ · NIH-10895391

This study is working on new ways to use light to better understand how proteins interact in our bodies, which could help us learn more about diseases like cancer and find new treatments for them.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWeill Medical Coll of Cornell Univ NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10895391 on NIH RePORTER

What this research studies

This research aims to enhance our understanding of protein interactions by developing new technologies that utilize light to improve the precision and resolution of protein mapping. By combining photocatalytic proximity labeling with advanced optical techniques, the researchers will create methods that allow for the identification of protein interactions at an unprecedented level of detail. Patients may benefit from this research as it could lead to new insights into disease mechanisms and potential therapeutic targets, particularly in cancer and other disorders. The project will unfold over five years, with the first half focused on technology development and the latter half on applying these innovations to real biological systems.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with cancers or other diseases where protein interactions play a significant role in disease progression.

Not a fit: Patients with conditions unrelated to protein interactions or those not involved in the biological processes being studied may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating various diseases, including cancers, by revealing critical protein interactions.

How similar studies have performed: Other research has shown success in using advanced optical techniques for protein mapping, indicating that this approach has the potential for significant advancements.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions CancersDisease
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.