Mapping how Parkinson's Disease affects brain networks involved in movement and cognition
Official title: Precision mapping of Parkinson's Disease pathophysiology in the Somato-Cognitive Action Network’s DBS targets
Funded at Washington University · NIH-11024715 · Data updated 2026-11-12
This study is looking at how certain brain networks affect movement and thinking in people with Parkinson's Disease, hoping to find ways to improve treatments like Deep Brain Stimulation to help make daily life easier for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | January 1, 2025 |
| Project end | December 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $613,897 |
| NIH project number | 1R01NS140256-01 |
| Project ID | NIH-11024715 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Parkinson's Disease who experience motor and cognitive symptoms.
✕Less likely to help
Patients with Parkinson's Disease who do not exhibit significant motor or cognitive symptoms may not benefit from this research.
What this research studies
This research investigates the underlying brain networks involved in Parkinson's Disease (PD), particularly focusing on the Somato-Cognitive Action Network (SCAN) that influences movement and cognitive functions. By utilizing advanced noninvasive imaging techniques, the study aims to understand how dysfunction in these networks contributes to symptoms like bradykinesia, gait freezing, and autonomic disturbances. Patients with PD may benefit from insights gained about how to better target treatments such as Deep Brain Stimulation (DBS) to improve their quality of life.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for managing Parkinson's Disease symptoms and improving patient mobility and cognitive function.
How similar studies have gone: Previous research has shown promising results in understanding brain networks related to movement disorders, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Gordon, Evan M. — Washington University
- Study coordinator: Gordon, Evan M.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.