Mapping how gut bacteria evolve in real-time
Quantitative approaches for mapping the real-time evolution of the gut microbiota
This study is looking at how quickly the bacteria in our gut can change and how those changes might affect our health, especially when it comes to things like antibiotic resistance and personalized treatments, so that patients can get better care based on how their gut bacteria respond to what they eat and the medicines they take.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10850715 on NIH RePORTER |
What this research studies
This research investigates the rapid evolution of gut microbiota, focusing on how genetic changes in these microbial communities can occur within days or months. By combining biophysical and population genetic modeling, the study aims to develop computational tools that can predict how these changes affect health, particularly in relation to antibiotic resistance and personalized therapies like fecal microbiome transplants. Patients may benefit from a better understanding of how their gut bacteria respond to diet and medications, potentially leading to more effective treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with gastrointestinal disorders or those undergoing treatments that affect gut microbiota.
Not a fit: Patients with stable gut microbiota and no gastrointestinal issues may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing gut health and combating antibiotic resistance.
How similar studies have performed: Other research has shown promising results in understanding gut microbiota dynamics, indicating that this approach could yield valuable insights.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Good, Benjamin H — Stanford University
- Study coordinator: Good, Benjamin H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.