Mapping how glucose metabolism works in living human cells
Official title: 4D functional mapping of glucose metabolism in Living Cells
Funded at University of Maryland Baltimore County · NIH-10647705 · Data updated 2026-11-12
This study is looking at how our cells use sugar for energy and how tiny parts of the cells work together over time, which could help us learn more about diseases like diabetes and cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore County NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | July 1, 2019 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $320,199 |
| NIH project number | 5R01GM134086-05 |
| Project ID | NIH-10647705 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with metabolic disorders, such as diabetes, or those affected by cancers that alter glucose metabolism.
✕Less likely to help
Patients with stable metabolic conditions that do not involve glucose metabolism or those not affected by cancer may not benefit from this research.
What this research studies
This research investigates the complex interactions of glucose metabolism and mitochondrial function in human cells by using advanced 4D imaging techniques. It aims to understand how different metabolic pathways are spatially organized and how they function together over time. By examining the arrangement of enzymes involved in glucose metabolism, the study seeks to uncover how these processes adapt to the needs of the cell. This could lead to new insights into metabolic diseases and cancer.
Why it matters
Potential benefit: If successful, this research could provide new strategies for treating metabolic disorders and cancers by targeting specific metabolic pathways.
How similar studies have gone: Previous research has shown promising results in understanding metabolic pathways, but this approach using 4D mapping is relatively novel and untested.
Where this research is happening
-
University of Maryland Baltimore County
Baltimore, United States Active
Researchers
- Principal investigator: Kyoung, Minjoung — University of Maryland Baltimore County
- Study coordinator: Kyoung, Minjoung
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.