Mapping how gene regulators work in developing frog embryos
Spatiotemporal mapping of enhancer activity in developing frog embryos
['FUNDING_R21'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10686937
This study is looking at how certain parts of DNA help control how genes work while frog embryos are developing, which could help us understand important processes for healthy growth.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-10686937 on ClinicalTrials.gov |
What this research studies
This research investigates how specific regions of DNA, known as enhancers, control gene expression during the development of frog embryos. By using advanced techniques, the researchers aim to measure the activity of these enhancers at different stages of development. The study focuses on understanding how these enhancers work together to regulate genes in a precise manner. This could provide insights into the fundamental processes of gene regulation that are crucial for proper development.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in the genetic mechanisms of development, particularly those with a background in biology or genetics.
Not a fit: Patients with no interest in genetic research or those not engaged in biological sciences may not find direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of gene regulation, which may lead to advancements in developmental biology and potential therapeutic strategies for genetic disorders.
How similar studies have performed: Other research has shown success in using model organisms to study gene regulation, indicating that this approach has potential for valuable insights.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHO, KEN W.Y. — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: CHO, KEN W.Y.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.