Mapping How Exercise Changes Our Bodies
Official title: ProMoTr: A Proteomics Center for MoTrPAC
Funded at Battelle Pacific Northwest Laboratories · NIH-11163402 · Data updated 2026-11-12
This project helps us understand the detailed ways physical activity affects proteins in human muscle and fat tissues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Pacific Northwest Laboratories NIH-funded |
| Lab location | 1 site (Richland, United States) |
| Project start | December 8, 2016 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $1,349,999 |
| NIH project number | 4U24DK112349-08 |
| Project ID | NIH-11163402 on NIH RePORTER |
Who could benefit from this research
✓Could help
This project analyzes tissue samples from adults participating in the larger MoTrPAC consortium who engage in physical activity.
✕Less likely to help
Patients not involved in the MoTrPAC consortium or those who do not provide tissue samples for analysis would not directly benefit from this specific research.
What this research studies
We know exercise is good for us, but exactly how it works at a molecular level is still a mystery. This project aims to uncover these secrets by looking closely at proteins and their modifications in muscle and fat tissues from people who engage in physical activity. By analyzing these samples, we can create a "molecular map" that shows how physical activity leads to health benefits. This work focuses on understanding the signals within cells, especially how proteins are modified after exercise.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of how exercise improves health, potentially guiding new strategies for disease prevention and treatment.
How similar studies have gone: While the health benefits of physical activity are well-established, this project uses advanced proteomics to provide a novel, comprehensive molecular understanding of these changes.
Where this research is happening
-
Battelle Pacific Northwest Laboratories
Richland, United States Active
Researchers
- Principal investigator: Adkins, Joshua N. — Battelle Pacific Northwest Laboratories
- Study coordinator: Adkins, Joshua N.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.