Mapping how cancer treatments distribute in the body using advanced imaging techniques
Official title: In Vivo 3-D Multi-Isotope Autoradiography of Radiopharmaceutical Therapy
Funded at Johns Hopkins University · NIH-11038837 · Data updated 2026-11-12
This study is looking at new ways to make cancer treatment better by creating special medicines that can find and target tumors more effectively, using small animals to see how well these treatments work and how safe they are.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | December 11, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $581,723 |
| NIH project number | 1R01CA297470-01 |
| Project ID | NIH-11038837 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with metastatic cancers who may benefit from advanced radiopharmaceutical therapies.
✕Less likely to help
Patients with localized cancers or those not eligible for radiopharmaceutical therapy may not receive benefits from this research.
What this research studies
This research focuses on improving cancer treatment by developing new radiopharmaceuticals that can target tumors more effectively. It uses advanced imaging techniques to measure how these treatments distribute within the organs and tumors of small animals, which helps in understanding their effectiveness and safety. By examining the microscale distribution of these therapies, the research aims to provide insights into optimizing cancer treatment protocols. The goal is to enhance the precision of radiopharmaceutical therapy, particularly for metastatic cancers.
Why it matters
Potential benefit: If successful, this research could lead to more effective and targeted cancer treatments, improving outcomes for patients with metastatic cancers.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for cancer treatment, indicating that this approach could lead to significant advancements in the field.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Du, Yong — Johns Hopkins University
- Study coordinator: Du, Yong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.