Mapping how aging affects cells using advanced software
Development of machine learning software to quantitatively map telomere induced senescence in tissue sections during aging
['FUNDING_OTHER'] · MAYO CLINIC ROCHESTER · NIH-10919225
This study is all about using smart computer programs to better understand how our cells age, which can help us learn more about aging and related health issues, and it’s designed for anyone interested in how aging affects our bodies.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MAYO CLINIC ROCHESTER (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-10919225 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding cellular senescence, a key factor in aging and age-related diseases, by developing advanced machine learning software. The project aims to enhance the detection and mapping of telomere-associated foci (TAF) in human tissue sections, which are indicators of cellular aging. By utilizing innovative technologies, the researchers will improve the accuracy and efficiency of TAF analysis, allowing for a better understanding of how aging impacts cellular health. This work will involve collaboration with Tissue Mapping Centers to customize the software for specific human tissues and integrate it with advanced imaging techniques.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing age-related health issues or those interested in the biological processes of aging.
Not a fit: Patients with acute conditions unrelated to aging or cellular senescence may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools for age-related diseases and improved understanding of cellular aging.
How similar studies have performed: Previous research has shown promise in using machine learning for biological analysis, indicating potential success for this novel approach.
Where this research is happening
ROCHESTER, UNITED STATES
- MAYO CLINIC ROCHESTER — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PASSOS, JOAO — MAYO CLINIC ROCHESTER
- Study coordinator: PASSOS, JOAO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.