Mapping genetic variants that affect brain function in autism and other disorders.
Functional mapping of noncoding regulatory variants in human neuronal subtypes3.
This study is looking at how certain genetic differences might affect the chances of developing conditions like autism, with the hope that understanding these factors can lead to better treatments for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11020977 on NIH RePORTER |
What this research studies
This research investigates how specific genetic variants in non-coding regions of the genome may influence the risk of developing neuropsychiatric disorders like autism spectrum disorder (ASD). By utilizing advanced genetic techniques and multidisciplinary approaches, the study aims to uncover the biological mechanisms behind these variants and their impact on neuronal function. Patients may benefit from a better understanding of the genetic factors contributing to their conditions, which could lead to more targeted and effective treatments in the future.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with autism spectrum disorder or other neuropsychiatric conditions who are interested in understanding the genetic factors related to their condition.
Not a fit: Patients without a diagnosis of autism spectrum disorder or related neuropsychiatric conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with autism and related neuropsychiatric disorders.
How similar studies have performed: Other research has shown promise in understanding the role of genetic variants in neuropsychiatric disorders, making this approach both relevant and potentially impactful.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Yang, Nan — Icahn School of Medicine at Mount Sinai
- Study coordinator: Yang, Nan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.