Mapping genetic modifications and proteins in DNA using advanced sequencing techniques
Multiomic genomic mapping with long read sequencing
This study is looking at how changes in DNA and proteins affect how our genes work, using a special technology that can read longer pieces of DNA, which could help doctors find better ways to diagnose and treat health conditions.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Epicypher, INC. NIH-funded |
| Lab location | 1 site (Research Triangle Park, UNITED STATES) |
| Project ID | NIH-10917165 on NIH RePORTER |
What this research studies
This research focuses on using advanced long-read sequencing technology to map genetic modifications and proteins associated with DNA. By analyzing longer segments of DNA, the study aims to provide a clearer understanding of how these modifications affect gene expression and cellular behavior. This approach allows researchers to investigate complex genomic regions that were previously difficult to study, potentially leading to new insights in biomedical research and drug development. Patients may benefit from improved diagnostic and therapeutic strategies based on these findings.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that involve complex genetic and epigenetic factors, such as cancer or genetic disorders.
Not a fit: Patients with conditions that do not involve significant genetic or epigenetic components may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnostics and targeted therapies for various diseases by enhancing our understanding of genetic and epigenetic factors.
How similar studies have performed: Other research has shown promising results using long-read sequencing technologies, indicating potential for significant advancements in genomic mapping.
Where this research is happening
Research Triangle Park, UNITED STATES
- Epicypher, INC. — Research Triangle Park, United States (Active)
Researchers
- Principal investigator: Burg, Jonathan Michael — Epicypher, INC.
- Study coordinator: Burg, Jonathan Michael
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.