Mapping genetic factors related to Alzheimer's Disease and brain imaging
Efficient IBD mapping for Alzheimer's Disease and related brain imaging phenotypes
This study is looking at how our genes might influence Alzheimer's Disease to help find better ways to diagnose and treat it, and it's designed for anyone interested in understanding more about this condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10803982 on NIH RePORTER |
What this research studies
This research investigates the genetic factors associated with Alzheimer's Disease (AD) by utilizing identical-by-descent (IBD) segments to enhance the understanding of genetic risk. The team will develop advanced statistical and computational methods to analyze large genetic datasets, specifically focusing on brain imaging phenotypes. By identifying novel genomic regions linked to AD, the research aims to provide insights that could lead to improved diagnostic and therapeutic strategies for patients. The findings will be shared publicly to encourage further research in this area.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of Alzheimer's Disease or those exhibiting early signs of cognitive decline.
Not a fit: Patients without a genetic predisposition to Alzheimer's Disease or those who are not experiencing cognitive issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potentially new treatments for Alzheimer's Disease.
How similar studies have performed: Previous research has shown promise in using genetic mapping techniques to identify risk factors for Alzheimer's Disease, indicating that this approach could yield valuable insights.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Chen, Han — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Chen, Han
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.