Mapping genes related to inflammatory bowel disease in African Americans
Official title: IBD Gene Mapping by Clinical and Population Subset
Funded at Rutgers Biomedical and Health Sciences · NIH-10888262 · Data updated 2026-11-12
This study is looking at how genes might affect inflammatory bowel disease (IBD), like Crohn’s disease and ulcerative colitis, specifically in African Americans, and it invites patients with IBD to share their genetic information to help find better treatments.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project start | September 30, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $467,327 |
| NIH project number | 5U01DK062431-23 |
| Project ID | NIH-10888262 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are African American individuals diagnosed with inflammatory bowel disease.
✕Less likely to help
Patients who do not identify as African American or those without a diagnosis of inflammatory bowel disease may not benefit from this research.
What this research studies
This research investigates the genetic factors contributing to inflammatory bowel disease (IBD), specifically Crohn’s disease and ulcerative colitis, within the African American population. By collaborating with multiple genetics research centers, the study aims to identify genetic variations and their impact on disease expression and progression. Patients with IBD will be recruited to provide genetic samples and detailed health information, which will be analyzed using advanced techniques like genome-wide association studies (GWAS). The goal is to enhance understanding of IBD genetics and improve patient outcomes through targeted therapies.
Why it matters
Potential benefit: If successful, this research could lead to better-targeted treatments and improved management strategies for African American patients suffering from inflammatory bowel disease.
How similar studies have gone: Previous research has successfully identified genetic loci associated with IBD in diverse populations, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Rutgers Biomedical and Health Sciences
Newark, United States Active
Researchers
- Principal investigator: Brant, Steven R — Rutgers Biomedical and Health Sciences
- Study coordinator: Brant, Steven R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.