Mapping early changes in lung adenocarcinoma to improve patient outcomes
Official title: The Pulmonary Pre-malignancy Atlas in the Lung Adenocarcinoma Spectrum
Funded at VA Greater Los Angeles Healthcare System · NIH-10950350 · Data updated 2026-11-12
This study is looking at how lung adenocarcinoma, a common type of lung cancer, changes early on to help doctors figure out which tumors are more aggressive and how best to treat them, using genetic tests and advanced imaging techniques.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA Greater Los Angeles Healthcare System NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | October 1, 2022 |
| Project end | September 30, 2026 |
| Funding year | 2025 |
| NIH project number | 5I01BX005721-03 |
| Project ID | NIH-10950350 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with early-stage lung adenocarcinoma, particularly those who have undergone lung cancer screening.
✕Less likely to help
Patients with advanced-stage lung cancer or those without a diagnosis of lung adenocarcinoma may not benefit from this research.
What this research studies
This research investigates the early changes in lung adenocarcinoma, a common type of lung cancer, to better understand how it behaves and responds to treatment. By analyzing genetic mutations and using advanced imaging techniques, the study aims to identify which tumors are more aggressive and which are less so. This information could help doctors make more informed decisions about patient management and treatment options. The research involves collecting and analyzing data from lung cancer screenings and long-term follow-ups.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for patients with lung adenocarcinoma.
How similar studies have gone: Previous research has shown promise in using genetic profiling and imaging to predict tumor behavior, indicating that this approach could be effective.
Where this research is happening
-
VA Greater Los Angeles Healthcare System
Los Angeles, United States Active
Researchers
- Principal investigator: Tran, Linh M — VA Greater Los Angeles Healthcare System
- Study coordinator: Tran, Linh M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.