Mapping cellular aging in mouse tissues to identify biomarkers
The Jackson Laboratory Senescence Tissue Mapping Center (JAX-Sen TMC) - Biological Analysis Core
This study is looking at mouse tissues to find signs of aging at the cellular level, which could help us understand how aging affects our bodies and lead to better treatments for people as they get older.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jackson Laboratory NIH-funded |
| Lab location | 1 site (Bar Harbor, United States) |
| Project ID | NIH-10894257 on NIH RePORTER |
What this research studies
This research focuses on analyzing mouse tissues to identify biomarkers associated with cellular aging, known as senescence. By utilizing advanced techniques, the project aims to create detailed atlases that map the cellular and molecular characteristics of aging tissues. The study involves high-resolution imaging and data collection from genetically diverse mouse models, allowing for a comprehensive understanding of how aging affects different tissues. Patients may benefit from insights gained about cellular aging that could inform future therapies or interventions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals interested in age-related conditions or those with a family history of age-associated diseases.
Not a fit: Patients with acute conditions unrelated to aging or cellular senescence may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the identification of new biomarkers for aging, potentially guiding the development of therapies to improve health in older adults.
How similar studies have performed: Previous research has shown promise in identifying biomarkers of aging in various models, suggesting that this approach could yield valuable insights.
Where this research is happening
Bar Harbor, United States
- Jackson Laboratory — Bar Harbor, United States (Active)
Researchers
- Principal investigator: Robson, Paul — Jackson Laboratory
- Study coordinator: Robson, Paul
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.