Mapping cellular aging in mouse tissues
Biological Analysis Core
['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-10894302
This study is looking at how cells age in different parts of the body in male and female mice, using special technology to see how these aging cells interact with each other, which could help us understand more about aging and its impact on health.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10894302 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a detailed map of cellular aging, known as senescence, in various tissues of male and female mice throughout their lifespan. By utilizing advanced single-cell and imaging technologies, the team aims to identify and characterize senescent cells and their interactions within the tissue environment. The study will leverage existing mouse aging projects and innovative computational methods to analyze and interpret the data, providing insights into the biological processes of aging. This comprehensive approach may help in understanding how aging affects health and disease.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would be individuals interested in the biological mechanisms of aging and age-related diseases.
Not a fit: Patients with conditions unrelated to aging or those who do not have a biological basis for cellular senescence may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding of aging-related diseases and potential therapeutic targets for age-related conditions.
How similar studies have performed: Other research has shown success in mapping cellular aging and its implications, indicating that this approach has potential for meaningful advancements.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BAKER, DARREN — JOHNS HOPKINS UNIVERSITY
- Study coordinator: BAKER, DARREN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.