Mapping cellular aging in mouse tissues
The Jackson Laboratory Senescence Tissue Mapping Center (JAX-Sen TMC) - Data Analysis Core
['FUNDING_OTHER'] · JACKSON LABORATORY · NIH-10894259
This study is all about making detailed maps of aging cells in mice to help us understand how aging affects our bodies, which could eventually lead to better insights for people dealing with age-related health issues.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JACKSON LABORATORY (nih funded) |
| Locations | 1 site (BAR HARBOR, UNITED STATES) |
| Trial ID | NIH-10894259 on ClinicalTrials.gov |
What this research studies
This research focuses on creating detailed maps and datasets that identify biomarkers of cellular senescence in various mouse tissues, including adipose tissue and organs like the kidney and heart. By utilizing advanced techniques in data analysis, imaging, and deep learning, the project aims to enhance our understanding of how aging affects cells at a molecular level. The findings will be shared with a broader consortium to standardize data processing and visualization, ultimately contributing to a comprehensive understanding of cellular aging. Patients may benefit indirectly through improved knowledge of aging-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit would be individuals interested in the biological mechanisms of aging and related health conditions.
Not a fit: Patients with acute conditions unrelated to aging or cellular senescence may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potential treatments for age-related diseases.
How similar studies have performed: Other research has shown promise in mapping cellular aging, indicating that this approach could yield valuable insights.
Where this research is happening
BAR HARBOR, UNITED STATES
- JACKSON LABORATORY — BAR HARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KORSTANJE, RONNY — JACKSON LABORATORY
- Study coordinator: KORSTANJE, RONNY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.