Mapping cellular aging in human tissues
Washington University Senescence Tissue Mapping Center (WU-SN-TMC)
This study is looking at how aging cells that stop dividing can affect our health, using samples from different parts of the body, to help us understand age-related diseases and find new ways to treat them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10914201 on NIH RePORTER |
What this research studies
This research investigates cellular senescence, a state where cells stop dividing and can affect surrounding tissues. By using advanced technologies, the team will analyze human samples from various tissues, including bone marrow, breast, colon, and liver, to create detailed atlases of senescent cells. This will help identify the mechanisms and pathways involved in cellular aging, providing insights into how these processes impact health over time. Patients may benefit from a better understanding of age-related diseases and potential therapeutic targets.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with age-related conditions or those interested in the biological processes of aging.
Not a fit: Patients who are not experiencing age-related conditions or cellular senescence may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating age-related diseases by targeting cellular senescence.
How similar studies have performed: Previous research has shown promise in understanding cellular senescence, but this approach of creating detailed atlases is relatively novel.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Ding, Li — Washington University
- Study coordinator: Ding, Li
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.