Mapping cavitation during laser treatment for urinary stones
Official title: 3D real-time super-resolution cavitation mapping in laser lithotripsy of urinary stone disease
Funded at Duke University · NIH-11062459 · Data updated 2026-11-12
This study is testing a new way to make laser treatment for kidney stones better and safer by using special imaging to see how the treatment is working in real-time, which could help patients have quicker and more effective procedures.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | April 1, 2024 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $602,441 |
| NIH project number | 5R01DK139109-02 |
| Project ID | NIH-11062459 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with urinary stone disease who are considering or scheduled for laser lithotripsy.
✕Less likely to help
Patients who do not have urinary stones or those who are not candidates for laser lithotripsy may not benefit from this research.
What this research studies
This research focuses on improving the treatment of urinary stone disease by using advanced imaging techniques to visualize cavitation bubbles during laser lithotripsy. The study aims to develop a 3D real-time super-resolution mapping system that can provide immediate feedback on cavitation activities, which are crucial for effectively breaking down urinary stones. By optimizing the laser settings based on this real-time data, the research seeks to enhance the efficiency and safety of the laser treatment process for patients. This innovative approach could lead to shorter procedure times and better outcomes for individuals undergoing this common treatment.
Why it matters
Potential benefit: If successful, this research could lead to more effective and efficient treatments for urinary stone disease, reducing recovery times and improving patient outcomes.
How similar studies have gone: Previous research has shown promising results with advanced imaging techniques in other medical applications, suggesting potential success for this novel approach in urinary stone treatment.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: Yao, Junjie — Duke University
- Study coordinator: Yao, Junjie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.