Mapping cancer driver networks to understand tumor mutations
Project 1: Systematic Physical and Spatial Mapping of Cancer Driver Networks
This study is looking at how different changes in tumor genes work together in cancer and aims to find out more about the proteins involved, which could help create more personalized treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10911939 on NIH RePORTER |
What this research studies
This research investigates the complex mutations found in tumors and how they interact within specific cancer pathways. By combining advanced imaging techniques and genomic data, the project aims to identify and characterize the networks of proteins that drive cancer development. This systematic mapping will help in understanding the unique mutations present in different tumors, which can lead to more targeted and effective cancer therapies. Patients may benefit from insights gained about their specific cancer pathways, potentially leading to personalized treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with various types of cancer who have complex mutational profiles.
Not a fit: Patients with early-stage cancers that do not exhibit significant mutational complexity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments based on individual tumor profiles.
How similar studies have performed: Other research has shown success in mapping cancer pathways, indicating that this approach has the potential for significant advancements in cancer treatment.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Lundberg, Emma — University of California, San Francisco
- Study coordinator: Lundberg, Emma
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.