Mapping brain networks that support human thinking and behavior
CRCNS: Multifocal causal mapping of brain networks supporting human cognition
['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10837871
This study is looking at how different parts of the brain work together to help us think and solve problems, and it involves patients doing tasks while we check their brain activity to learn more about how our brains control our actions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10837871 on ClinicalTrials.gov |
What this research studies
This research investigates how different areas of the brain interact to support complex cognitive functions. By using advanced neuroimaging techniques and transcranial magnetic stimulation (TMS), the study aims to create temporary 'virtual lesions' in multiple brain regions simultaneously. This approach will help researchers understand the causal relationships between brain activity and behavior, potentially leading to new insights into cognitive processes. Patients may be involved in tasks that assess their cognitive functions while their brain activity is monitored.
Who could benefit from this research
Good fit: Ideal candidates for participation would include individuals with cognitive impairments or those interested in understanding brain function related to cognition.
Not a fit: Patients with severe neurological disorders that prevent participation in cognitive tasks may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of cognitive disorders by revealing how brain networks contribute to human cognition.
How similar studies have performed: Previous research using TMS and neuroimaging has shown promise in understanding brain function, suggesting that this approach could yield valuable insights.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NUMMENMAA, AAPO — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: NUMMENMAA, AAPO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.