Mapping brain networks in aging and Alzheimer's disease
Official title: Precision Mapping of Functional Networks in Healthy and Pathological Aging
Funded at Northwestern University · NIH-10973479 · Data updated 2026-11-12
This study is looking at how the brain works in older adults, both healthy ones and those with Alzheimer's, using special brain scans to see how their brain activity changes with age and disease, which could help improve diagnosis and treatment in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project start | September 1, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $44,439 |
| NIH project number | 1F99AG088569-01 |
| Project ID | NIH-10973479 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are healthy older adults aged 60-75 and younger adults aged 18-30.
✕Less likely to help
Patients with severe cognitive impairment or those outside the specified age ranges may not benefit from this research.
What this research studies
This research investigates how brain networks function in both healthy aging and Alzheimer's disease using advanced imaging techniques. By employing functional Magnetic Resonance Imaging (fMRI), the study aims to identify individual-specific brain network patterns in older adults compared to younger adults. Participants will undergo multiple fMRI sessions to gather detailed data on their brain activity, which will help researchers understand how these networks change with age and disease. The goal is to enhance our understanding of brain function in aging and Alzheimer's, potentially leading to better diagnostic and therapeutic strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for Alzheimer's disease and age-related cognitive decline.
How similar studies have gone: Previous research using similar fMRI techniques has shown promise in understanding brain network changes, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Northwestern University
Chicago, United States Active
Researchers
- Principal investigator: Perez Rivera, Diana Carolina — Northwestern University
- Study coordinator: Perez Rivera, Diana Carolina
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.