Mapping brain function to understand recovery from aphasia after stroke
Functional anomaly mapping of aphasia recovery
['FUNDING_OTHER'] · GEORGETOWN UNIVERSITY · NIH-10896310
This study is looking at how a stroke affects the brain's ability to communicate, especially for those with aphasia, by using a new technique to see which parts of the brain aren't working well, so we can better understand how to help with recovery.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | GEORGETOWN UNIVERSITY (nih funded) |
| Locations | 1 site (WASHINGTON, UNITED STATES) |
| Trial ID | NIH-10896310 on ClinicalTrials.gov |
What this research studies
This research investigates how brain function changes after a stroke that causes aphasia, a condition that affects communication. It uses a novel machine learning technique called functional anomaly mapping (FAM) to analyze brain activity through resting BOLD functional MRI scans. By identifying areas of the brain that are not functioning properly, the study aims to understand how these dysfunctions impact recovery from aphasia. This approach goes beyond traditional methods by considering both direct and indirect effects of stroke on brain function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a left-hemisphere stroke resulting in aphasia.
Not a fit: Patients who have not had a stroke or those with aphasia due to causes other than stroke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for rehabilitation and recovery for patients with aphasia.
How similar studies have performed: Previous research has shown that understanding brain function through advanced imaging techniques can significantly enhance recovery strategies, suggesting this approach has potential for success.
Where this research is happening
WASHINGTON, UNITED STATES
- GEORGETOWN UNIVERSITY — WASHINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DEMARCO, ANDREW T — GEORGETOWN UNIVERSITY
- Study coordinator: DEMARCO, ANDREW T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.