Mapping brain connectivity in Parkinson's disease
Official title: Precision-Mapping Functional Connectivity in Parkinson's Disease
Funded at Washington University · NIH-11000767 · Data updated 2026-11-12
This study is looking at how the brains of people with Parkinson's disease connect differently than those of healthy individuals, with the hope of finding clues that can help tailor treatments and predict how the disease might progress for each person.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | February 1, 2023 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $549,076 |
| NIH project number | 5R01NS124738-03 |
| Project ID | NIH-11000767 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Parkinson's disease who are experiencing a range of motor and non-motor symptoms.
✕Less likely to help
Patients with Parkinson's disease who are in very early stages or those with atypical forms of the disease may not benefit from this research.
What this research studies
This research investigates how brain connectivity patterns differ in individuals with Parkinson's disease compared to healthy individuals. Using advanced imaging techniques, the study aims to identify specific brain network markers that correlate with the symptoms and progression of the disease. By focusing on individual-level differences, the research seeks to enhance personalized treatment approaches for patients. The goal is to develop reliable biomarkers that can help predict cognitive and motor outcomes in Parkinson's disease.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment strategies for patients with Parkinson's disease.
How similar studies have gone: Other research has shown promise in using brain connectivity mapping to understand neurological conditions, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: Campbell, Meghan C — Washington University
- Study coordinator: Campbell, Meghan C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.