Mapping brain connections using advanced imaging techniques

BRAIN CONNECTS: The center for Large-scale Imaging of Neural Circuits (LINC)

['FUNDING_OTHER'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10913361

This study is working on new ways to take detailed pictures of brain connections in both monkeys and humans, which could help us understand how the brain works and improve treatments for brain disorders, all without any invasive procedures.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10913361 on ClinicalTrials.gov

What this research studies

This research aims to develop and validate new imaging technologies to visualize axonal projections in the brain, focusing on both macaque and human brains. By employing three innovative microscopy techniques, the project will create detailed maps of brain connections, which are crucial for understanding brain function and disorders. Patients may benefit from insights gained about brain connectivity that could inform future treatments for neurological conditions. The research will involve advanced imaging methods that do not require invasive procedures.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with neurological conditions or those interested in brain health and connectivity.

Not a fit: Patients with conditions unrelated to brain connectivity or those who do not wish to participate in imaging studies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a better understanding of brain connectivity, potentially improving treatments for neurological disorders.

How similar studies have performed: Other research has shown success in using advanced imaging techniques to study brain connectivity, indicating a promising approach.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.