Mapping brain connections in children with drug-resistant epilepsy
Noninvasive Mapping of Functional and Effective Connectivity in Children with Drug Resistant Epilepsy
['FUNDING_R01'] · COOK CHILDREN'S MEDICAL CENTER · NIH-11031315
This study is looking at safe ways to understand how different parts of the brain connect in kids with hard-to-treat epilepsy, so we can create better treatment plans and improve their care without needing any surgery.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COOK CHILDREN'S MEDICAL CENTER (nih funded) |
| Locations | 1 site (FORT WORTH, UNITED STATES) |
| Trial ID | NIH-11031315 on ClinicalTrials.gov |
What this research studies
This research investigates noninvasive methods to map brain connectivity in children suffering from drug-resistant epilepsy. By using advanced electrophysiological techniques, the study aims to identify the brain regions involved in seizure activity without the need for invasive procedures like intracranial EEG. The goal is to create detailed brain maps that can help in understanding the networks responsible for seizures, potentially leading to better treatment options and improved outcomes for patients. This approach seeks to enhance surgical planning and minimize risks associated with traditional methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0 to 21 years who are diagnosed with drug-resistant epilepsy.
Not a fit: Patients whose epilepsy is well-controlled with medication may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for children with drug-resistant epilepsy, improving their chances of becoming seizure-free.
How similar studies have performed: Other research has shown promise in using noninvasive techniques for mapping brain activity, indicating that this approach could be a valuable advancement in epilepsy treatment.
Where this research is happening
FORT WORTH, UNITED STATES
- COOK CHILDREN'S MEDICAL CENTER — FORT WORTH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PAPADELIS, CHRISTOS — COOK CHILDREN'S MEDICAL CENTER
- Study coordinator: PAPADELIS, CHRISTOS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.