Mapping brain circuits using advanced X-ray imaging techniques
Brain-wide Neuronal Circuit Mapping with X-ray Nano-Holography
This study is exploring new X-ray imaging techniques to create clear pictures of brain connections, helping us understand how these circuits affect decision-making, which could lead to better treatments for neurological conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10914312 on NIH RePORTER |
What this research studies
This research aims to develop cutting-edge X-ray imaging technologies to create detailed maps of neuronal circuits in the brain. By utilizing a powerful synchrotron source, the study will enhance imaging resolution to visualize connections between neurons over large areas of the brain. The approach combines non-destructive imaging with traditional methods to ensure accuracy and will focus on understanding how specific brain circuits contribute to decision-making processes. Patients may benefit from insights gained about brain function and potential treatments for neurological conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological conditions that affect decision-making and sensory processing.
Not a fit: Patients with conditions unrelated to brain circuitry or those who do not have neurological disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding brain function and developing new treatments for neurological disorders.
How similar studies have performed: Other research has shown success in mapping brain circuits using advanced imaging techniques, indicating a promising avenue for this novel approach.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Kuan, Aaron — Yale University
- Study coordinator: Kuan, Aaron
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.