Mapping brain blood flow in newborns to understand brain development

Time-resolved laser speckle contrast imaging of resting-state functional connectivity in neonatal brain

NIH-funded research Biopticstechnology, LLC · NIH-10950843

This study is testing a new, non-invasive imaging technique to help doctors see how blood flows in the brains of newborns, which can help them spot and treat brain injuries early on.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBiopticstechnology, LLC NIH-funded
Lab location1 site (Lexington, United States)
Project IDNIH-10950843 on NIH RePORTER

What this research studies

This research focuses on developing a new imaging technology to monitor blood flow in the brains of newborns, which is essential for identifying and managing brain injuries early. The approach uses time-resolved laser speckle contrast imaging (TR-LSCI) to provide high-resolution images of cerebral blood flow across different brain regions without the need for invasive procedures. By capturing data in real-time, this method aims to improve our understanding of how brain connectivity develops in infants, potentially leading to better treatment strategies for those with brain injuries.

Who could benefit from this research

Good fit: Ideal candidates for this research are newborns, particularly those at risk for brain injuries or developmental issues.

Not a fit: Patients who are older children or adults, or those without any history of brain injury, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier diagnosis and improved management of brain injuries in newborns, ultimately enhancing their long-term health outcomes.

How similar studies have performed: Similar imaging technologies have shown promise in other studies, indicating that this approach could be effective in monitoring brain development.

Where this research is happening

Lexington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.