Mapping brain activity changes in Alzheimer's Disease
Brain entropy mapping in Alzheimer's Disease
['FUNDING_R01'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-11075574
This study is looking at how brain activity changes in people with Alzheimer's compared to those who are healthy, hoping to find early signs of the disease before symptoms show up, which could help with better detection and understanding of Alzheimer's.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MARYLAND BALTIMORE (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11075574 on ClinicalTrials.gov |
What this research studies
This research investigates how brain activity, measured through a concept called functional brain entropy (fBEN), changes in individuals with Alzheimer's Disease (AD) compared to healthy aging. By analyzing existing brain imaging data, the study aims to identify patterns that could indicate early signs of AD before symptoms appear. The researchers will develop advanced tools to analyze this data, potentially leading to better understanding and early detection of the disease. This approach could help bridge the gap between brain changes and clinical symptoms in Alzheimer's.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults, particularly those showing early signs of cognitive decline or those at risk for Alzheimer's Disease.
Not a fit: Patients with advanced Alzheimer's Disease or those with other forms of dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection of Alzheimer's Disease, allowing for timely interventions and improved patient outcomes.
How similar studies have performed: Previous research using similar brain imaging techniques has shown promise in understanding Alzheimer's Disease, suggesting that this approach could yield valuable insights.
Where this research is happening
BALTIMORE, UNITED STATES
- UNIVERSITY OF MARYLAND BALTIMORE — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, ZE — UNIVERSITY OF MARYLAND BALTIMORE
- Study coordinator: WANG, ZE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia