Mapping brain activity and cognition across different species
Official title: An Alignment Framework For Mapping Brain Dynamics and Substrates of Human Cognition Across Species
Funded at Child Mind Institute, INC. · NIH-10360863 · Data updated 2026-11-12
This study looks at how the brains of macaque monkeys can help us understand how human brains work, using special imaging tools to compare brain structures and functions, which could give us new insights into how we think and learn.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Child Mind Institute, INC. NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 13, 2021 |
| Project end | September 12, 2025 |
| Funding year | 2021 |
| Award (this year) | $1,210,696 |
| NIH project number | 1RF1MH128696-01 |
| Project ID | NIH-10360863 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with neurological conditions or cognitive impairments who could gain from advancements in brain mapping techniques.
✕Less likely to help
Patients with conditions unrelated to brain function or those who do not have access to advanced imaging technologies may not receive direct benefits from this research.
What this research studies
This research investigates how brain dynamics and cognitive functions in humans can be understood by studying non-human primates, particularly macaques. By using advanced imaging techniques like fMRI, the researchers aim to create a framework that aligns brain structures and functions across species. This approach allows for a detailed comparison of brain organization, which can enhance our understanding of human cognition. The study utilizes large publicly available MRI datasets to support its findings.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of human brain function and cognition, potentially informing new treatments for neurological disorders.
How similar studies have gone: Previous research has shown success in using non-human primate models to inform human brain studies, making this approach both promising and grounded in established methodologies.
Where this research is happening
-
Child Mind Institute, INC.
New York, United States Active
Researchers
- Principal investigator: Xu, Ting — Child Mind Institute, INC.
- Study coordinator: Xu, Ting
Related research
Other NIH-funded projects on the same topics.
-
Cognition After War: A new {HCAP} for older adults and their children
A study will create a standardized cognitive test battery for older veterans and their midlife children to understand how early-life war exposure might influence dementia risk.
-
Cognition After War: A New, Harmonized Cognitive Check for Older Adults and Their Children
A new program will create a standardized set of cognitive tests and study how early-life war experiences might raise dementia risk in older adults and potentially affect their midlife children.
-
Cognition After War: A New, Harmonized Cognitive Test Series and ADRD Risk Study for Older Adults and Their Children
A study will create a harmonized set of cognitive tests and look at how early-life war exposure may relate to dementia risk in older adults and their midlife children.
-
Cognition after war: a new, harmonized brain-health check for older adults and their children
A new plan will create a harmonized set of cognitive tests and study how early-life war exposure might influence later dementia risk in older adults and their midlife children.
-
ROMA:Cog trial compares single vs multiple arterial grafts for brain health after CABG
A study in adults undergoing heart bypass surgery will test whether one arterial graft or multiple arterial grafts affect brain function and brain injury markers.
-
SynGAP1: New Ways It Shapes Synapses and Thinking
A Johns Hopkins team is studying how a protein called SynGAP1 helps brain connections and thinking, to understand autism-related changes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.