Mapping blood flow in the developing infant brain
Infant Atlas of Brain Perfusion
This study is looking to create a detailed map of how blood flows in babies' brains to help us understand what healthy brain development looks like and how certain brain disorders might affect it, using a safe imaging technique that doesn't hurt the little ones.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11030716 on NIH RePORTER |
What this research studies
This research aims to create a detailed three-dimensional atlas of blood flow in the brains of infants, which is crucial for understanding both normal brain development and the impact of brain disorders. By using a noninvasive imaging technique called arterial spin labeling MRI, researchers will measure regional cerebral blood flow in infants to establish a reference for healthy brain function. This atlas will help identify abnormalities in blood flow associated with conditions like stroke or ischemia, providing insights into their effects on brain development and function.
Who could benefit from this research
Good fit: Ideal candidates for this research include infants who are at risk for or have experienced brain injuries or disorders.
Not a fit: Patients who are older children or adults will likely not benefit from this specific research focused on infant brain development.
Why it matters
Potential benefit: If successful, this research could lead to better diagnosis and treatment strategies for brain disorders in infants.
How similar studies have performed: Previous research has successfully utilized similar imaging techniques to study brain function, suggesting that this approach may yield valuable insights.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Huang, Hao — Children's Hosp of Philadelphia
- Study coordinator: Huang, Hao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.