Mapping and regulating temperature within cells
Nanoscale Temperature Mapping and Thermal Regulation of Intracellular Dynamics
This study is looking at how temperature changes affect the way our cells work, using tiny tools to measure and control temperature at a very small level, which could help us understand more about how temperature impacts health and diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10898008 on NIH RePORTER |
What this research studies
This research investigates how temperature affects cellular functions by developing advanced nanoscale tools that can both measure and manipulate temperature at the sub-cellular level. By creating precise nanoarchitectures, the project aims to explore how cells detect and respond to temperature changes, which is crucial for their survival and function. The methodology involves combining these nano-tools with sophisticated imaging and modeling techniques to gain insights into the thermal dynamics of cellular processes. Patients may benefit from a deeper understanding of how temperature regulation impacts various diseases and cellular functions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions that affect cellular function or metabolism.
Not a fit: Patients with stable conditions that do not involve cellular dysfunction or temperature sensitivity may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that enhance cellular function and treat diseases linked to temperature regulation.
How similar studies have performed: While the specific approach of nanoscale temperature mapping is innovative, similar research has shown promise in understanding cellular responses to temperature changes.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Hu, Yongjie — University of California Los Angeles
- Study coordinator: Hu, Yongjie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.