Mapping and identifying aging cells in human tissues
Senescent cell mapping, identification and validation for human somatic and reproductive tissues
This study is looking at special cells that stop dividing and can affect how we age and develop diseases, focusing on tissues like the ovary, breast, and muscles, to help find new ways to treat age-related health issues like cancer and neurodegeneration.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Buck Institute for Research on Aging NIH-funded |
| Lab location | 1 site (Novato, United States) |
| Project ID | NIH-10895599 on NIH RePORTER |
What this research studies
This research investigates the presence and characteristics of senescent cells, which are cells that have stopped dividing and can influence aging and age-related diseases. By focusing on human tissues such as the ovary, breast, and skeletal muscle, the study aims to understand how these cells affect tissue function and contribute to conditions like cancer and neurodegeneration. The research employs a combination of biological analysis and data mapping to identify when and where these cells occur, as well as how their behavior changes with age. Patients may benefit from insights that could lead to new treatments targeting age-related pathologies.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults experiencing age-related health issues or those with conditions linked to cellular aging.
Not a fit: Patients who are younger and do not have age-related conditions may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating age-related diseases.
How similar studies have performed: Other research has shown promising results in understanding cellular senescence and its implications for aging, indicating that this approach has potential for significant advancements.
Where this research is happening
Novato, United States
- Buck Institute for Research on Aging — Novato, United States (Active)
Researchers
- Principal investigator: Schilling, Birgit — Buck Institute for Research on Aging
- Study coordinator: Schilling, Birgit
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.