Mapping and analyzing healthy human tissues to understand cellular aging
Data-Analysis-Core
This study is working on creating a detailed map of healthy human tissues to learn more about aging and how certain cells change over time, which could help improve treatments for age-related conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10899785 on NIH RePORTER |
What this research studies
This research focuses on creating a detailed atlas of healthy human tissues, including adipose, liver, skeletal muscle, and ovarian tissues, to study senescent cells and their characteristics. The Data Analysis Core will utilize advanced bioinformatics and data management techniques to analyze samples from various age groups, ensuring high-quality data is collected and interpreted. By integrating single-cell data and employing predictive modeling, the project aims to provide insights into cellular dynamics and aging processes. Patients may benefit from improved understanding of age-related changes in tissues, which could inform future treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are healthy individuals across a range of ages who are willing to provide tissue samples for analysis.
Not a fit: Patients with existing severe health conditions or those who are not willing to participate in tissue sampling may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding how aging affects human tissues, potentially guiding new therapies for age-related conditions.
How similar studies have performed: Other research in the field of bioinformatics and tissue mapping has shown promise, indicating that this approach could yield valuable insights.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Aliferis, Constantin F. — University of Minnesota
- Study coordinator: Aliferis, Constantin F.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.