Mapping aging cells in human tissues like ovaries and breast
Senescence tissue mapping and SASP Atlas for human somatic and reproductive tissues
This study is looking at how certain cells in the ovaries, breast tissue, and muscles change as we age, and it aims to create detailed maps of these changes to help us find better treatments for age-related health issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Buck Institute for Research on Aging NIH-funded |
| Lab location | 1 site (Novato, United States) |
| Project ID | NIH-10895600 on NIH RePORTER |
What this research studies
This research focuses on identifying and mapping senescent cells in key human tissues, specifically ovaries, breast tissue, and skeletal muscle. By creating detailed tissue maps and a SASP Atlas, the project aims to understand how these tissues age and the biological markers associated with cellular senescence. The research involves collaboration among various scientific cores to streamline tissue collection and data analysis, ultimately enhancing our understanding of aging in these critical areas. Patients may benefit from insights that could lead to improved treatments for age-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing age-related changes or conditions affecting their ovaries, breast tissue, or skeletal muscle.
Not a fit: Patients with no age-related conditions or those outside the targeted tissue areas may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potential treatments for age-related diseases affecting reproductive and somatic tissues.
How similar studies have performed: Other research has shown promise in mapping cellular aging, indicating that this approach could yield valuable insights.
Where this research is happening
Novato, United States
- Buck Institute for Research on Aging — Novato, United States (Active)
Researchers
- Principal investigator: Hansen, Malene — Buck Institute for Research on Aging
- Study coordinator: Hansen, Malene
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.