Manufacturing and stability testing of a drug for treating parasitic infections
Official title: Task C13: GMP Manufacturing of Oxfendazole Clinical Trial Material and Stability Study
Funded at Sri International · NIH-11250920 · Data updated 2026-11-12
This study is working on a new medicine called Oxfendazole to help treat infections from parasites like the pork tapeworm, and if it works well in tests, it could be a helpful option for patients in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sri International NIH-funded |
| Lab location | 1 site (Menlo Park, United States) |
| Project start | May 1, 2018 |
| Project end | November 15, 2025 |
| Funding year | 2025 |
| Award (this year) | $72,349 |
| NIH project number | 272201800001I-P00005-759302100006-1 |
| Project ID | NIH-11250920 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from infections caused by parasitic diseases, particularly those related to T. solium.
✕Less likely to help
Patients with non-parasitic infections or those not affected by T. solium may not receive any benefit from this research.
What this research studies
This research focuses on the development and manufacturing of Oxfendazole, a drug aimed at treating infections caused by parasitic diseases such as those caused by the pork tapeworm. The project involves creating clinical trial materials under Good Manufacturing Practices (GMP) and conducting stability studies to ensure the drug remains effective over time. Patients may benefit from the eventual availability of this treatment if it proves successful in clinical trials. The research employs both laboratory (in vitro) and animal (in vivo) testing to evaluate the drug's safety and effectiveness.
Why it matters
Potential benefit: If successful, this research could lead to a new effective treatment for parasitic infections, improving patient outcomes.
How similar studies have gone: Similar research efforts in developing treatments for infectious diseases have shown promise, indicating a potential for success in this area.
Where this research is happening
-
Sri International
Menlo Park, United States Active
Researchers
- Principal investigator: Mirsalis, Jon — Sri International
- Study coordinator: Mirsalis, Jon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.