NIH-funded research NIH-funded research

Mantram Repetition Program for Veterans with PTSD and Chronic Pain

Official title: Randomized Controlled Trial of Mantram Repetition Program Versus Health and Wellness Psychoeducation for Veterans with Comorbid Posttraumatic Stress Disorder and Chronic Pain

Funded at VA San Diego Healthcare System · NIH-11401142 · Data updated 2026-11-12

A VA study will test a meditation-based program to help veterans who have both PTSD and chronic pain feel better and sleep better, compared with standard health education.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA San Diego Healthcare System
NIH-funded
Lab location1 site (San Diego, United States)
Project startOctober 1, 2026
Project endSeptember 30, 2030
Funding year2026
NIH project number1I01RD001563-01A2
Project IDNIH-11401142 on NIH RePORTER

Who could benefit from this research

Could help

Veterans with both PTSD and chronic non-malignant pain who are receiving VA care.

Less likely to help

Some participants may not experience meaningful improvements in pain or PTSD symptoms.

What this research studies

This project invites veterans with PTSD and chronic pain to participate in a randomized trial comparing the Mantram Repetition Program to a health and wellness education program. The team will measure outcomes like pain interference, sleep, and psychological well-being over time to see which approach helps more. The intervention uses silent repetition of a calming word plus focused attention and slower breathing to reduce arousal and distress. The study is led by the VA San Diego Health Care System and aims to be practical for real-world use within VA care. Participation could involve sessions, surveys, and tracking of symptoms with the goal of improving daily functioning.

Why it matters

Potential benefit: If successful, participants may experience less pain disruption, better sleep, and improved mood and functioning.

How similar studies have gone: Previous trials suggest MRP can help with PTSD and arousal, but testing in Veterans with comorbid pain is new.

Where this research is happening

  • VA San Diego Healthcare System
    San Diego, United States
    Active

Researchers

  • Principal investigator: Malaktaris, Anne — VA San Diego Healthcare System
  • Study coordinator: Malaktaris, Anne

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.