Managing weight loss and quality of life in pancreatic cancer patients

Managing metabolic disruption in pancreatic cancer to prevent weight loss and improve quality of life

NIH-funded research Sloan-Kettering Inst Can Research · NIH-10892257

This study is looking at how certain diabetes medications can help people with pancreatic cancer manage their blood sugar and maintain a healthy weight, making life a little easier for those dealing with weight loss and diabetes.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionSloan-Kettering Inst Can Research NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10892257 on NIH RePORTER

What this research studies

This research focuses on improving the quality of life for patients with pancreatic cancer by addressing metabolic disruptions that lead to weight loss and cachexia. It investigates the effectiveness of various anti-diabetic medications in managing hyperglycemia, which is common in these patients. By comparing the outcomes of different treatments, the research aims to identify the best options for maintaining healthy weight and managing blood sugar levels. This approach is particularly important as many pancreatic cancer patients experience both diabetes and weight loss, complicating their treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with pancreatic ductal adenocarcinoma who are experiencing weight loss and hyperglycemia.

Not a fit: Patients with pancreatic cancer who do not experience weight loss or hyperglycemia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved management of weight loss and better overall quality of life for pancreatic cancer patients.

How similar studies have performed: While there is limited comparative effectiveness research specifically in pancreatic cancer, similar approaches in other cancer types have shown promise in improving patient outcomes.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions anti-cancer treatment
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.