Managing kidney function in young children with spina bifida

Seattle Children's Urologic Management to Preserve Initial Renal Function Protocol for Young Children with Spina Bifida (UMPIRE Protocol) (Component C)

NIH-funded research Seattle Children's Hospital · NIH-11141526

This study is looking at a special plan to help keep kidneys healthy in young kids with spina bifida by closely watching their urinary health, so they can have better long-term health, and families will be involved to make sure the care fits each child's needs.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionSeattle Children's Hospital NIH-funded
Lab location1 site (Seattle, United States)
Project IDNIH-11141526 on NIH RePORTER

What this research studies

This research focuses on a protocol designed to help preserve kidney function in young children diagnosed with spina bifida. The approach involves careful monitoring and management of urologic health to prevent complications that could affect renal function. By utilizing a structured management plan, the research aims to improve the long-term health outcomes for these children. Families will be engaged in the process to ensure that care is tailored to the individual needs of each child.

Who could benefit from this research

Good fit: Ideal candidates for this research are young children diagnosed with spina bifida who are at risk for renal function decline.

Not a fit: Patients who do not have spina bifida or those whose renal function is already severely compromised may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved kidney health and overall quality of life for children with spina bifida.

How similar studies have performed: Previous research has shown that structured management protocols can effectively improve health outcomes in pediatric populations with similar conditions.

Where this research is happening

Seattle, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.