Managing funds for lung transplant tolerance research
Official title: Infrastructure and Opportunities Fund Management Core
Funded at Massachusetts General Hospital · NIH-11035227 · Data updated 2026-11-12
This study is looking at ways to help lung transplant patients by testing new methods to make their bodies accept the new lungs better, and it's being done with the help of nonhuman primates to find the best solutions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | March 23, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $659,958 |
| NIH project number | 5U19AI174967-03 |
| Project ID | NIH-11035227 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit would include individuals awaiting lung transplants or those who have received lung transplants and are seeking improved management of their condition.
✕Less likely to help
Patients who are not candidates for lung transplantation or those with conditions unrelated to lung allograft tolerance may not receive benefits from this research.
What this research studies
This research focuses on managing the Infrastructure and Opportunities Fund for a cooperative study aimed at achieving tolerance in lung allografts using nonhuman primates. The team will oversee the allocation and tracking of funds, establish an administrative framework, and report on project progress to ensure effective use of resources. Patients may benefit from advancements in transplantation tolerance that could improve outcomes for lung transplant recipients.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for lung transplant tolerance, potentially reducing the need for lifelong immunosuppression in patients.
How similar studies have gone: Previous research in transplantation tolerance has shown promising results, indicating that novel approaches in this area could lead to significant advancements.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Madsen, Joren C — Massachusetts General Hospital
- Study coordinator: Madsen, Joren C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.