Managing bladder health in young children with spina bifida

Urologic Management to Preserve Initial Renal Function Protocol for Young Children with Spina Bifida (UMPIRE) at Texas Children's Hospital/Baylor College of Medicine

NIH-funded research Baylor College of Medicine · NIH-11140935

This study is looking for better ways to help newborns with spina bifida manage their bladder health, so they can stay healthy and keep their kidneys working well.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionBaylor College of Medicine NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11140935 on NIH RePORTER

What this research studies

This research focuses on improving the urologic management of newborns diagnosed with spina bifida, a condition that can severely affect urinary tract function. The study aims to establish effective protocols for monitoring and treating these children to preserve their kidney function and overall health. It involves regular imaging and assessments, as well as interventions like clean intermittent catheterization and medications to support bladder function. By collecting and analyzing data over time, the research seeks to fill gaps in knowledge regarding the best practices for managing bladder health in this vulnerable population.

Who could benefit from this research

Good fit: Ideal candidates for this research are newborns diagnosed with spina bifida who require urologic management.

Not a fit: Patients without a diagnosis of spina bifida or those who are older than newborns may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better management strategies that preserve kidney function and improve the quality of life for children with spina bifida.

How similar studies have performed: While there is limited documentation on the outcomes of current management protocols for spina bifida, this research aims to provide new insights and data that could enhance existing practices.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.