Managing bladder health in young children with spina bifida

Component C. Urologic Management to Preserve Initial Renal Function Protocol for Young Children with Spina Bifida (UMPIRE Protocol)

NIH-funded research Children's Hospital of Los Angeles · NIH-11140934

This study is working to create a better care plan for young children with spina bifida to help keep their kidneys healthy and reduce issues like urinary tract infections, so they can enjoy a better quality of life.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionChildren's Hospital of Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-11140934 on NIH RePORTER

What this research studies

The UMPIRE Protocol focuses on implementing and evaluating a specialized urologic management plan for young children diagnosed with spina bifida. This research involves collecting data and analyzing outcomes to enhance the long-term renal health of these patients. By standardizing documentation and collaborating with other research sites, the study aims to improve care and outcomes for children affected by this condition. The protocol addresses common complications such as urinary tract infections and renal failure, which can significantly impact the quality of life for these children.

Who could benefit from this research

Good fit: Ideal candidates for this research are young children diagnosed with spina bifida, particularly those experiencing urologic complications.

Not a fit: Patients without spina bifida or those who do not have urologic issues related to their condition may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved kidney health and overall quality of life for young children with spina bifida.

How similar studies have performed: Previous research has shown that structured urologic management can lead to better outcomes in similar pediatric populations, indicating a promising approach.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.